Mesterolone for depression

Like other AAS, drostanolone is an agonist of the androgen receptor (AR). [3] It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity. [3] As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites . [3] While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives. [3] Since the drug is not 17α-alkylated , it is not known to cause hepatotoxicity . [3]

In one small scale clinical trial of depressed patients, an improvement of symptoms which included anxiety, lack of drive and desire was observed. [16] In patients with dysthymia , unipolar , and bipolar depression significant improvement was observed. [16] In this series of studies, mesterolone lead to a significant decrease in luteinizing hormone and testosterone levels. [16] In another study, 100 mg mesterolone cipionate was administered twice monthly. [17] With regards to plasma testosterone levels, there was no difference between the treated versus untreated group, and baseline luteinizing hormone levels were minimally affected. [17]

Q. How could one boost metabolism by diet? I am aware for long that metabolism is the cause for poor health and how could one boost metabolism by diet? A. Metabolism, if it is not erroneous genetically; then it can be controlled or increased by any diet. What matters is the timing and regularity you feed yourself which uses your hormones and enzymes in your body to do the task they are for. This timing and regularity depends on eating in same time regularly and working and sleeping too. To excite some hormones even if they had switched off their action in body, can be excited by exercise and feeding with small diets in regular short time intervals. To make all this happen, reduce on junk foods, please.

Mesterolone for depression

mesterolone for depression

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