Though Masteron holds a weaker androgenic strength rating than Testosterone itself, androgenic side effects are still indeed possible with this compound, especially among those who may be particularly sensitive. Masteron side effects that include androgenic side effects include: an increase in oily skin (as a result of increased sebum production/secretion), increased facial hair and bodily hair growth, as well as the increased risk of triggering MPB (Male Pattern Baldness) in those that are genetically sensitive or predisposed to it. Virilization (the development of male characteristics in women) is also a risk with female use, though its use in female breast cancer patients should attest to its acceptable nature as a female-use compound.
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Estrogen, which is the main enemy of breast cancer patients, is curbed through SERM and AI. Master also shares these characteristics and is capable of preventing estrogen buildup in the body. As DHT derivative, it does not allow aromatization and displays strong anti-aromatase properties. For this reason, Masteron has been used in combination with other drugs to treat breast cancer patients. The role of Masteron then was to block the amount of estrogens in the body while other drugs, such as Tamoxifen-citrate were used to block the binding of estrogen at the breast receptors. Today, many other more powerful aromatase inhibitors have replaced this breast cancer treatment to achieve even greater success in the fight against breast cancer.