Like other AAS, drostanolone is an agonist of the androgen receptor (AR).  It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity.  As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites .  While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives.  Since the drug is not 17α-alkylated , it is not known to cause hepatotoxicity . 
It was once claimed in a magazine article that Palmie “punched and gouged his way from Paris to Toulouse” even when playing against mates. Wales hooker Bobby Windsor, hardly a shrinking violet himself, described the former Beziers and France second row as the hardest men he ever played against. “He would have to be No1,” said Windsor. “He’d boot anyone, any time. He’d give a quick look round to make sure the ref wasn’t looking and then, bang.” Palmie’s playing career ended in 1978 when he was banned for life for punching Armand Clerc, leaving the Racing Club player partially blinded in one eye. Went on to become an official in the French Rugby Federation!