Anti-Parkinson Agents (Dopamine Agonist): May diminish the therapeutic effect of Antipsychotic Agents (First Generation [Typical]). Antipsychotic Agents (First Generation [Typical]) may diminish the therapeutic effect of Anti-Parkinson Agents (Dopamine Agonist). Management: Avoid concomitant therapy if possible and monitor for decreased effects of both agents when these combinations cannot be avoided. Atypical antipsychotics such as clozapine and quetiapine may be less likely to reduce the effects of anti-Parkinson agents. Consider therapy modification
Mood stabilizers like lithium ( Lithobid ) and antiseizure (anticonvulsant) medications like divalproex ( Depakote ), carbamazepine ( Tegretol , Tegretol XR), and lamotrigine ( Lamictal ) treat active manic or mixed symptoms and those symptoms from returning. Antidepressants are the primary medical treatment for the depressive symptoms of bipolar disorder. Antidepressants include selective serotonin reuptake inhibitor (SSRI) medications like fluoxetine ( Prozac ), sertraline ( Zoloft ), paroxetine ( Paxil ), citalopram ( Celexa ), escitalopram ( Lexapro ), vortioxetine (Trintellix), and vilazodone (Viibryd); serotonergic/adrenergic medications (SNRIs) like venlafaxine ( Effexor ), duloxetine ( Cymbalta ), desvenlafaxine ( Pristiq ), and levomilnacipran (Fetzima), as well as bupropion ( Wellbutrin ), a dopaminergic antidepressant .